The doctoral thesis studies the topic of the affirmation of the meaning of life in the realistic novels by Canadian Catholic author Michael D. O’Brien through Viktor Frankl’s logotherapy and existential analysis and the theological-philosophical approach of Christian anthropology. Through stories about the spiritual journey of an ordinary person, O’Brien explores metaphysical questions of discovering the meaning of life through deeds, love, faith, and the acceptance of suffering, while affirming the uniqueness and value of every human life and addressing the concepts of spirituality, freedom, responsibility, and conscience. Similarly to O’Brien’s novels, Christian theology and philosophy, as well as existential analysis and logotherapy, take the spiritual dimension of human beings as their starting point and deal with the question of the meaning of life, providing answers compatible to O’Brien’s. According to existential analysis and logotherapy, each person has the responsibility to discover the meaning of their life through self-transcendence, which is realized through deeds, experiences such as love, and their attitude toward inevitable suffering. Christianity provides an ontic foundation to this phenomenological manifestation of meaning. This foundation is God, who is love, so that, according to Christianity, the experience of meaning is in the experience of love, by which man is saved. Salvation thus represents the ultimate meaning of life. The aim of this research is to study, describe, and typify the affirmative elements that represent the meaning of life in Michael D. O’Brien’s realistic novels as well as to determine whether O’Brien’s novels belong to high or popular literature.