The aim of the research was to examine relationship between attachment styles, guilt, and hostility with severity of symptoms among people suffering from psoriasis. The study included 107 people diagnosed with psoriasis vulgaris. Adult Romantic Attachment Questionnaire (Kamenov and Jelić, 2003) was used to investigate the attachment styles. The experience of guilt was investigated by the Guilt Scale for Adolescents (Laskoski, Natividade and Hutz, 2013), the hostility toward self was measured with Differential Emotions Scale (Izard, Libero, Putnam and Haynes, 1993) while the severity of the disease was determined by the Psoriasis Area and Severity Index (PASI; Fredriksson and Pettersson, 1978). The data were analysed using analysis of variance and hierarchical regression analysis. The results indicate that there subjects with different attachment styles have different levels of symptom severity. The difference was found between subjects with secure and fearful and preoccupied and fearful attachment style. When examining a direct effect of the attachment styles on symptom severity, it was found that the only dimension that has a significant effect was attachment dimension of avoidance. When testing indirect effects of the attachment styles on severity of the symptoms through the experience of hostility and guilt, it has been shown that the dimension anxiety contributes to the symptoms through the experience of guilt and hostility, while dimension avoidance contributes through hostility only. Finally, results indicate that the differences in psoriasis symptoms depend upon differences in experience of hostility, but not guilt. Highly hostile participants have greater presence of psoriasis symptoms than ones with low hostility.